Alternatives for Dermal Toxicity Testing (Post nr. 301)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03282nam a22004815i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 61026 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200226102239.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171122s2017 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783319503530 |
| -- | 978-3-319-50353-0 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-319-50353-0 |
| Source of number or code | doi |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (DE-He213)978-3-319-50353-0 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RL1-803 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJK |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED017000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.5 |
| Edition number | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Alternatives for Dermal Toxicity Testing |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Chantra Eskes, Erwin van Vliet, Howard I. Maibach. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Cham : |
| Name of producer, publisher, distributor, manufacturer | Springer International Publishing : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2017. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XX, 592 p. 92 illus., 61 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Introduction -- Concepts -- Skin irritation -- Skin corrosion -- Skin sensitization -- UV-induced effects (phototoxicity & photoallergy) -- Skin genotoxicity -- Other exploratory areas of relevance. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol, possible adaptations, and challenges and opportunities. The closing section addresses exploratory areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, the use of alternative methods for infections and inflammatory diseases, novel complex skin models, and high-throughput screening techniques. Dermal toxicity is an area in which alternatives to the use of animal testing have already gained scientific, industrial, and regulatory acceptance. Practitioners and researchers alike will find Alternatives for Dermal Toxicity Testing to be an ideal source of reliable, up-to-date information on all aspects of the available test methods and likely future directions. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dermatology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animal models in research. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dermatology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacology/Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animal Models. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eskes, Chantra. |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | van Vliet, Erwin. |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maibach, Howard I. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9783319503516 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://dx.doi.org/10.1007/978-3-319-50353-0">http://dx.doi.org/10.1007/978-3-319-50353-0</a> |
| 912 ## - | |
| -- | ZDB-2-SME |
Inga exemplar finns tillgängliga.