Paroxysmal Nocturnal Hemoglobinuria (Post nr. 6304)

MARC-detaljer
000 -LEADER
fixed length control field	03612nam a22004575i 4500
001 - CONTROL NUMBER
control field	60558
005 - DATE AND TIME OF LATEST TRANSACTION
control field	20200226102527.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field	cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field	170116s2017 ja \| s \|\|\|\| 0\|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number	9784431560036
--	978-4-431-56003-6
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code	10.1007/978-4-431-56003-6
Source of number or code	doi
035 ## - SYSTEM CONTROL NUMBER
System control number	(DE-He213)978-4-431-56003-6
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number	RB45
072 #7 - SUBJECT CATEGORY CODE
Subject category code	MJF
Source	bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code	MED038000
Source	bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number	616.15
Edition number	23
245 10 - TITLE STATEMENT
Title	Paroxysmal Nocturnal Hemoglobinuria
Medium	[electronic resource] :
Remainder of title	From Bench to Bedside /
Statement of responsibility, etc.	edited by Yuzuru Kanakura, Taroh Kinoshita, Jun-ichi Nishimura.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture	Tokyo :
Name of producer, publisher, distributor, manufacturer	Springer Japan :
--	Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice	2017.
300 ## - PHYSICAL DESCRIPTION
Extent	VIII, 358 p. 71 illus., 46 illus. in color.
Other physical details	online resource.
336 ## - CONTENT TYPE
Content type term	text
Content type code	txt
Source	rdacontent
337 ## - MEDIA TYPE
Media type term	computer
Media type code	c
Source	rdamedia
338 ## - CARRIER TYPE
Carrier type term	online resource
Carrier type code	cr
Source	rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type	text file
Encoding format	PDF
Source	rda
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note	1 A History of Research of PNH: Defining a Disease -- Part I Basic Sciences in PNH -- 2 Synthesis, genetics and congenital diseases of GPI-anchored proteins -- 3 Animal models of paroxysmal nocturnal hemoglobinuria -- 4 Complement and PNH -- Part II Clinical Sciences in PNH -- 5 Epidemiology in PNH: The PNH Global Registry -- 6 Epidemiology in PNH; Clinical Epidemiological Studies in Korea -- 7 Hemolysis in PNH; Depletion of nitric oxide -- 8 Bone Marrow Failure in PNH -- 9 Thrombophilia in PNH -- 10 Diagnosis and Classification of PNH -- 11 Clinical significance of a small population of glycosyl phosphatidylinositol-anchored membrane proteins (GPI-APs)-deficient cells in the management of bone marrow failure -- 12 CLONAL ORIGIN AND CLONAL SELECTION IN PNH -- 13 Pathogenesis of clonal dominance in PNH: Selection mechanisms in PNH -- 14 Pathogenesis of Clonal Dominance in PNH; Growth Advantage in PNH -- 15 Clinical Management in PNH -- 16 CLINICAL EFFECTS OF ECULIZUMAB IN PNH -- 17 Clinical Effects of Eculizumab in PNH; Extravascular Hemolysis after Eculizumab Treatment -- 18 Clinical Effects of Eculizumab in PNH; Poor-Responders to Eculizumab -- 19 Hematopoietic Stem Cell Transplantation in PNH -- 20 Future strategies of complement inhibition in paroxysmal nocturnal hemoglobinuria -- 21 Pregnancy in paroxysmal nocturnal hemoglobinuria.
520 ## - SUMMARY, ETC.
Summary, etc.	This volume reviews the fundamental understanding of this potentially life-threatening disease and the advances in treatment that have been achieved with the use of the monoclonal antibody eculizumab. Although the PIGA gene has been known for many years, the mechanism of clonal dominance in paroxysmal nocturnal hemoglobinuria is still largely unknown. This book, Paroxysmal Nocturnal Hemoglobinuria, discusses the direction of continuing research in this area, as well as the potential for the development of management guidelines. It serves as a valuable source of information for both basic scientists and physicians, especially immunologists targeting GPI-anchored proteins and complements, and hematologists specializing in bone marrow failure.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Immunology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Hematology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Medicine & Public Health.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Hematology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Immunology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name	Kanakura, Yuzuru.
Relator term	editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name	Kinoshita, Taroh.
Relator term	editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name	Nishimura, Jun-ichi.
Relator term	editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element	SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title	Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information	Printed edition:
International Standard Book Number	9784431560012
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier	<a href="http://dx.doi.org/10.1007/978-4-431-56003-6">http://dx.doi.org/10.1007/978-4-431-56003-6</a>
912 ## -
--	ZDB-2-SME

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