The Blood Brain Barrier and Inflammation (Post nr. 8086)
[ visa ren ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 03910nam a22005535i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 60206 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200226102620.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170329s2017 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783319455143 |
| -- | 978-3-319-45514-3 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-319-45514-3 |
| Source of number or code | doi |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (DE-He213)978-3-319-45514-3 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QR180-189.5 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJCM |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED044000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.079 |
| Edition number | 23 |
| 245 14 - TITLE STATEMENT | |
| Title | The Blood Brain Barrier and Inflammation |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Ruth Lyck, Gaby Enzmann. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Cham : |
| Name of producer, publisher, distributor, manufacturer | Springer International Publishing : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2017. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | VI, 286 p. 32 illus., 24 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Progress in Inflammation Research |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | General Introduction to Barrier Mechanisms in the Central Nervous System -- Topological Aspects of the Blood-brain and Blood cerebrospinal Fluid Barriers and their Relevance in Inflammation Research -- The Contribution of the Extracellular Matrix to the BBB in Steady State and Inflammatory Conditions -- Pathophysiology of the Bloodbrain Barrier in Neuroinflammatory Diseases -- Leakage at Blood-neural Barriers -- Blood-Brain Barrier Transporters and Neuroinflammation: Partners in Neuroprotection and in Pathology -- MicroRNAs in Brain Endothelium and Inflammation -- Blood-Brain Barrier Dysfunction during Central Nervous System Autoimmune Diseases -- Pathways Across the Blood Brain Barrier -- Neuroinflammation in Bacterial Meningitis -- Blood Vessels in the Brain: a Signaling Hub in Brain Tumor Inflammation. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Within the central nervous system (CNS) the constantly changing blood stream is separated from the CNS parenchyma by the blood brain barrier (BBB) restricting passage to selected immune cells. Under pathological conditions, however, viruses, bacteria, parasites and autoaggressive immune cells can penetrate the barrier and contribute to CNS inflammation. The BBB actively contributes to neuroinflammation by presentation of chemokines, expression of cell adhesion molecules and alteration of barrier properties. As such, understanding the role of the BBB under healthy and pathological conditions is essential for the development of new drugs to efficiently combat inflammatory diseases of the CNS. This book presents a comprehensive collection of reviews that focus on the role of the BBB. Experts in the field share their insight on structural, topological and functional properties of the BBB. They elaborate on pathophysiological changes of the inflamed BBB such as permeability, transporter proteins and alterations in microRNAs and cytokine profile. Additional chapters on multiple sclerosis and bacterial meningitis provide in depth information on significant neuroinflammatory diseases. The selection is complemented by a review on the current understanding of the BBB as signaling hub in tumor pathogenesis in the brain. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Immunology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neurosciences. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Infectious diseases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cytokines. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Growth factors. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell membranes. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Immunology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neurosciences. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Membrane Biology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Infectious diseases. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cytokines and Growth Factors. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lyck, Ruth. |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Enzmann, Gaby. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9783319455129 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Progress in Inflammation Research |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://dx.doi.org/10.1007/978-3-319-45514-3">http://dx.doi.org/10.1007/978-3-319-45514-3</a> |
| 912 ## - | |
| -- | ZDB-2-SME |
Inga exemplar finns tillgängliga.