The CAPRISA Clinical Trials: HIV Treatment and Prevention (Post nr. 8091)

MARC-detaljer
000 -LEADER
fixed length control field 05214nam a22004935i 4500
001 - CONTROL NUMBER
control field 60245
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20200226102620.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170120s2017 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783319475189
-- 978-3-319-47518-9
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-3-319-47518-9
Source of number or code doi
035 ## - SYSTEM CONTROL NUMBER
System control number (DE-He213)978-3-319-47518-9
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RA427.8
072 #7 - SUBJECT CATEGORY CODE
Subject category code MBN
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED076000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 613
Edition number 23
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 614.44
Edition number 23
245 14 - TITLE STATEMENT
Title The CAPRISA Clinical Trials: HIV Treatment and Prevention
Medium [electronic resource] /
Statement of responsibility, etc. edited by Quarraisha Abdool Karim, Salim S. Abdool Karim, Cheryl Baxter.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Cham :
Name of producer, publisher, distributor, manufacturer Springer International Publishing :
-- Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice 2017.
300 ## - PHYSICAL DESCRIPTION
Extent VI, 243 p. 24 illus., 23 illus. in color.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Part I. Introduction -- Studies Linked to the Evolving HIV Epidemic in South Africa: Informing the CAPRISA Scientific Agenda -- CAPRISA: Establishing A Research Center to Undertake HIV Clinical Trials -- Overview of Clinical Trials -- Part II. CAPRISA Clinical Trials for HIV and HSV-2 Prevention -- Antiretrovirals for HIV Prevention -- Rolling out of tenofovir gel in family planning clinics: the CAPRISA 008 implementation trial -- Conditional cash transfers to reduce HIV risk in young women: the CAPRISA 007 cluster randomised control trial -- HIV vaccine and passive immunity trials -- Part III: CAPRISA Clinical Trials for HIV–TB Treatment -- CAPRISA 003: Timing of antiretroviral initiation in HIV-TB co-infected patients - The SAPiT Trial -- Scaling up TB-HIV integration in public health clinics: translating research findings into practice -- Part IV: Experiences and lessons learnt from clinical trials in CAPRISA -- Lessons from the Acute Infection Study: from Bench to Bedside -- Understanding sexual HIV transmission in women by focusing on the genital mucosa -- Part V: Essential support activities for the conduct of clinical trials -- Good practices in conducting clinical trials: Good Participatory Practice, Good Pharmacy Practice and Good Laboratory Practice -- Grants Management -- Taking science to the people: communication and media strategies for clinical trials -- Looking ahead: What Does the Future Hold for CAPRISA? -- Appendix -- Index. .
520 ## - SUMMARY, ETC.
Summary, etc. Since its inception 14 years ago, CAPRISA has conducted numerous clinical studies that have influenced international TB-HIV treatment guidelines as well as HIV prevention through innovations in the microbicide and vaccine fields. This book provides a historical account of how each of CAPRISA’s high impact studies was created, developed, implemented, analysed and communicated. In doing so, the reader is taken on a journey that provides glimpses into the genesis of research ideas and how this ultimately leads to a range of HIV prevention and treatment studies that have impacted the global response to the HIV and TB epidemics. Comprised of 5 sections, the book details the following: HIV epidemic in South Africa and the establishment of a research centre to undertake clinical, epidemiological and laboratory research on HIV. CAPRISA’s clinical trials on HIV and HSV-2 prevention. These studies investigated the impact of tenofovir gel as topical antiretroviral pre-exposure prophylaxis (PrEP), implementation of topical PrEP through family planning clinics, conditional cash incentives for HIV prevention, HIV vaccines, and passive immunisation with broadly neutralising antibodies. CAPRISA’s research on the treatment of HIV and TB co-infection. A review of the major scientific findings from the CAPRISA studies on acute infection and genital mucosal immunology. Essential support activities for the conduct of clinical trials, including research laboratories and pharmacies, as well as establishing effective communication and sustainable structures for community engagement to maintain effective and respectful partnerships with participating communities. The book concludes with a chapter about the challenges facing future HIV prevention and treatment trials. The CAPRISA Clinical Trials: HIV Treatment and Prevention is a resource for undergraduate and postgraduate students, health care providers, doctors, decision-makers and researchers who are seeking guidance and insights on clinical trials – their creation, conduct and impact.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Health promotion.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Health informatics.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Infectious diseases.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Medicine & Public Health.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Health Promotion and Disease Prevention.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Infectious diseases.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Health informatics.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Abdool Karim, Quarraisha.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Abdool Karim, Salim S.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Baxter, Cheryl.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783319475172
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://dx.doi.org/10.1007/978-3-319-47518-9">http://dx.doi.org/10.1007/978-3-319-47518-9</a>
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-- ZDB-2-SME

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