The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease (Post nr. 8114)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04452nam a22004335i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 60214 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200226102621.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 161202s2017 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783319459509 |
| -- | 978-3-319-45950-9 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-319-45950-9 |
| Source of number or code | doi |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (DE-He213)978-3-319-45950-9 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC648-665.2 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJG |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED027000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.4 |
| Edition number | 23 |
| 245 14 - TITLE STATEMENT | |
| Title | The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease |
| Medium | [electronic resource] : |
| Remainder of title | Cushing’s Syndrome and Beyond / |
| Statement of responsibility, etc. | edited by Eliza B. Geer. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Cham : |
| Name of producer, publisher, distributor, manufacturer | Springer International Publishing : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2017. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | VI, 327 p. 19 illus., 15 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Part 1. Hypothalamic-pituitary-adrenal axis regulation of the body, brain, and inflammation -- 1. Glucocorticoid regulation of body composition and metabolism -- 2. Glucocorticoid regulation of neurocognitive and neuropsychiatric function -- 3. Glucocorticoids: Inflammation and Immunity -- Part 2. Cushing’s Syndrome -- 4. Pathogenesis, diagnosis and localization of Cushing’s: Molecular pathogenesis of primary adrenal Cushing’s syndrome -- . 5. Pathogenesis, diagnosis and localization of Cushing’s -- 5. Pathogenesis, diagnosis and localization of Cushing’s: Pathogenesis and treatment of aggressive corticotroph pituitary tumors - Yang Shen and Anthony P Heaney -- 6. Pathogenesis, diagnosis and localization of Cushing’s: Neoplastic/Pathologic and Non-neoplastic/Physiologic Hypercortisolism: Cushing verses Pseudo-Cushing Syndromes -- 7. Pathogenesis, diagnosis and localization of Cushing’s: Imaging strategies for localization of ACTH - secreting tumors -- 8. Recent Advances in the medical and surgical treatment of Cushing’s: Surgical Treatment of Cushing’s disease -- 9. Recent Advances in the medical and surgical treatment of Cushing’s: Medical therapies in Cushing’s syndrome -- 10. New themes in Cushing’s definitions and outcomes: Mild adrenal cortisol excess – 11. New themes in Cushing’s definitions and outcomes: Long term effects of prior Cushing’s syndrome -- 12. New themes in Cushing’s definitions and outcomes: Cushing’s disease: refining the definition of remission and recurrence -- Part 3. Beyond Cushing’s: Glucocorticoid sensitivity, regulation and the metabolic syndrome -- 13. Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis through a Mutated Glucocorticoid Receptor -- 14. Cortisol metabolism as a regulator of the tissue-specific glucocorticoid action -- 15. Obesity and metabolic syndrome: a phenotype of mild long-term hypercortisolism. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Cushing´s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Endocrinology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Systems biology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Endocrinology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Systems biology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Geer, Eliza B. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9783319459486 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://dx.doi.org/10.1007/978-3-319-45950-9">http://dx.doi.org/10.1007/978-3-319-45950-9</a> |
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| -- | ZDB-2-SME |
Inga exemplar finns tillgängliga.