I. Long Term Health Consequences of Restless Legs Syndrome/Willis-Ekbom Disease -- 1. Mental Health Disorders Associated with RLS -- 2. Sleep Impact: Insomnia, Hypersomnia, Sleep Attacks, and Circadian Disorders -- 3. Cognitive Functioning -- 4. Health Related Quality of Life and Depression/Anxiety Symptom Measures for the Assessment of Treatment in Restless Legs Syndrome/Willis-Ekbom Disease -- 5. Epidemiologic Evidence in Cardiovascular Disease -- 6. Heart Rate and Blood Pressure Changes Associated with Periodic Limb Movements -- 7. Willis-Ekbom Disease, Periodic Limb Movements of Sleep, and Cardiovascular Disease: Putative Mechanisms and Implications for Long-Term Treatment -- 8. Peripheral Muscle Changes -- 9. Outcome and Mortality in Renal Failure-Related RLS -- II. Long Term Management of Restless Legs Syndrome/Willis-Ekbom Disease -- 10. Long Term Pharmacological Treatment -- 11. Augmentation: Criteria, Prevalence, and Differential Diagnosis -- 12. Treatment Options When Short-Acting Dopamine Agonists Fail or Cause Augmentation: Switching or Adding Medications -- 13. Management of Augmentation -- 14. Managing Concurrent Medications -- 15. Impulsive Behaviors: Definition, Prevalence, Neurobiology, and Management -- 16. Impulse Control Behavior in Movement Disorders: Focus on Restless Leg Syndrome -- 17. Management of RLS During Pregnancy -- 18. Management of RLS in Children (Unique Features).

Due to the fact that Restless Legs Syndrome/Willis-Ekbom Disease is usually a chronic condition, this book aims to provide physicians with the necessary tools for the long-term management of patients with RLS. The first part of the book addresses the various comorbidities and long-term consequences of RLS on life quality, sleep, cognitive, psychiatric and cardiovascular systems, while the second part focuses on the management of long-term treatment and the drug-induced complications in primary RLS and in special populations. Written by experts in the field, this practical resource offers a high-quality, long-term management of RLS for neurologists, sleep clinicians, pulmonologists and other healthcare professionals.