Ex Vivo Engineering of the Tumor Microenvironment  [electronic resource] / 
edited by Amir R. Aref, David Barbie. 
 - IX, 135 p. 18 illus., 17 illus. in color.  online resource. 
 - Cancer Drug Discovery and Development,  2196-9906 .
 - Cancer Drug Discovery and Development, .
<br/><br/>1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy. . 
<br/><br/> This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time. 
<br/><br/><label>ISBN: </label>9783319453972 
<br/><br/><label>Standard No.: </label>10.1007/978-3-319-45397-2  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Medicine.<br/>Cancer research.<br/>Biomedicine.<br/>Cancer research.
<br/><br/><label>LC Class. No.: </label>RC261-271 
<br/><br/><label>Dewey Class. No.: </label>614.5999