TY - BOOK AU - Tozer,Thomas N. AU - Rowland,Malcolm TI - Essentials of pharmacokinetics and pharmacodynamics SN - 9781451194425 AV - RM301.5 U1 - 615.7 23/swe PY - 2016///] CY - Philadelphia PB - Wolters Kluwer Health KW - Farmakokinetik KW - sao KW - Pharmacokinetics KW - Dose-Response Relationship, Drug KW - Drug Therapy KW - methods KW - Pharmaceutical Preparations KW - administration & dosage KW - Farmakodynamik KW - Läkemedelseffekter KW - Läkemedelsterapi KW - Pharmacodynamics KW - Drug effects KW - Drug therapy N1 - Preceded by Introduction to pharmacokinetics and pharmacodynamics : the quantitative basis of drug therapy / Thomas N. Tozer, Malcolm Rowland. c2006; Includes index; Ej fjärrlån; Input-exposure relationships -- Exposure-response relationships -- Membranes : a determining factor -- Quantifying events following an intravenous bolus -- Physiologic and physicochemical determinants of distribution and elimination -- Quantifying events following an extravascular dose -- Physiologic and physicochemical determinants of drug absorption -- Response following a single dose -- Therapeutic window -- Constant-rate regimens -- Multiple-dose regimens -- Variability -- Initiating and managing therapy N2 - This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text ER -