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008 161107s2017 gw | s |||| 0|eng d
020 _a9783319465272
_9978-3-319-46527-2
024 7 _a10.1007/978-3-319-46527-2
_2doi
035 _a(DE-He213)978-3-319-46527-2
050 4 _aRC705-779
072 7 _aMJL
_2bicssc
072 7 _aMED079000
_2bisacsh
082 0 4 _a616.2
_223
245 1 0 _aAcute Lung Injury and Repair
_h[electronic resource] :
_bScientific Fundamentals and Methods /
_cedited by Lynn M. Schnapp, Carol Feghali-Bostwick.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Humana Press,
_c2017.
300 _aVIII, 185 p. 23 illus., 20 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aRespiratory Medicine,
_x2197-7372
505 0 _aMethods to Study Lung Injury and Repair -- Mouse Models of Acute Lung Injury -- Transgenic Animal Models in Lung Research -- Fundamental Methods for Analysis of Acute Lung Injury in Mice -- Invasive Measurement of Pulmonary Function in Mice -- Analysis of Epithelial Injury and Repair -- Flow Cytometric Evaluation of Acute Lung Injury and Repair -- Lung Imaging in Animal Models -- Genetic and Genomic Approaches to Acute Lung Injury -- MicroRNA Analysis in Acute Lung Injury.
520 _aAcute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies.
650 0 _aMedicine.
650 0 _aCritical care medicine.
650 0 _aRespiratory organs
_xDiseases.
650 1 4 _aMedicine & Public Health.
650 2 4 _aPneumology/Respiratory System.
650 2 4 _aIntensive / Critical Care Medicine.
700 1 _aSchnapp, Lynn M.
_eeditor.
700 1 _aFeghali-Bostwick, Carol.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319465258
830 0 _aRespiratory Medicine,
_x2197-7372
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-46527-2
912 _aZDB-2-SME
999 _c105
_d105