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020 _a9783319531687
_9978-3-319-53168-7
024 7 _a10.1007/978-3-319-53168-7
_2doi
035 _a(DE-He213)978-3-319-53168-7
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
245 1 0 _aCell Biology of Herpes Viruses
_h[electronic resource] /
_cedited by Klaus Osterrieder.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2017.
300 _aVII, 224 p. 18 illus., 9 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Anatomy, Embryology and Cell Biology,
_x0301-5556 ;
_v223
505 0 _aInitial contact: The first steps in herpesvirus entry -- Herpesvirus capsid assembly and DNA packaging -- Interindividual spread of herpesviruses -- Innate immune mechanisms and herpes simplex virus infection and disease -- Herpesvirus latency. On the importance of positioning oneself -- The human CMV IE1 protein: An offender of PML nuclear bodies -- Assembly and egress of an alphaherpesvirus clockwork -- Herpes simplex virus membrane fusion. .
520 _aHerpes viruses are widely distributed in nature, causing disease in organisms as diverse as bivalves and primates, including humans. Each virus appears to have established a long-standing relationship with its host, and the viruses have the ability to manipulate and control the metabolism of host cells, as well as innate and adaptive antiviral immune responses. Herpes viruses maintain themselves within hosts in a latent state resulting in virus persistence for years – usually for the life span of the hosts. Herpes viruses comprise a large number of pathogens with diverse cellular targets and biological consequences of infection. What they have in common is their structure and the fact that they establish a dormant (latent) infection in their hosts that usually persists for life. The reviews here will highlight the general principles of herpes virus infection, with equal attention to overall principle and important difference. Also, the cell type- and life-style dependent differences in the establishment and maintenance of virus persistence will be covered.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aVirology.
650 0 _aCell biology.
650 1 4 _aBiomedicine.
650 2 4 _aVirology.
650 2 4 _aImmunology.
650 2 4 _aCell biology.
700 1 _aOsterrieder, Klaus.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319531670
830 0 _aAdvances in Anatomy, Embryology and Cell Biology,
_x0301-5556 ;
_v223
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-53168-7
912 _aZDB-2-SME
999 _c1226
_d1226