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007			cr nn 008mamaa
008			170106s2017 ja | s |||| 0|eng d
020			_a9784431560593 _9978-4-431-56059-3
024	7		_a10.1007/978-4-431-56059-3 _2doi
035			_a(DE-He213)978-4-431-56059-3
050		4	_aRD592.5-596
072		7	_aMNN _2bicssc
072		7	_aMED085010 _2bisacsh
082	0	4	_a617.48 _223
245	1	0	_aCell Therapy Against Cerebral Stroke _h[electronic resource] : _bComprehensive Reviews for Translational Researches and Clinical Trials / _cedited by Kiyohiro Houkin, Koji Abe, Satoshi Kuroda.
264		1	_aTokyo : _bSpringer Japan : _bImprint: Springer, _c2017.
300			_aX, 156 p. 15 illus., 11 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPart I. Optimal Cell Sources -- 1. Bone Marrow-Derived Mononuclear Cells -- 2. Mesenchymal Stem Cells / Bone Marrow Stromal Cells -- 3. Neural Stem Cells / Neuronal Progenitor Cells -- 4. iPS Cells / iN -- Part II. Translational Research -- 5. Cell Culture -- 6. Cell Dose, Timing and Route -- 7. Scaffold -- 8. Cell Tracking -- 9. Functional Bio-Imaging -- Part III. Clinical Trials -- 10. Review of Previous Clinical Trials and Guideline of Cell Therapy -- 11. Bone Marrow-Derived Mononuclear Cells -- 12. Mesenchymal Stem Cells.
520			_aThis book presents comprehensive reviews for both translational research and clinical trials on cell therapy for stroke. Cerebral stroke is still a leading cause of death and disability. However, despite intensive research, few treatment options are available. The therapeutic potential of cell transplantation has been studied for various pathological conditions of the central nervous system (CNS) including traumatic brain injury, traumatic spinal cord injury, degenerative disease, demyelinating disease and ischemic stroke, as the injured neural tissue in the CNS has only a limited regenerative capacity. Recently, a growing body of evidence in this field suggests that cell transplantation holds great potential as a form of stroke therapy. The authors, who are experts in the field of neurosurgery, review and discuss optimal cell sources and various issues involved in translational research; further, they outline ongoing clinical trials in Japan.
650		0	_aMedicine.
650		0	_aNeurology.
650		0	_aNeurosurgery.
650		0	_aRegenerative medicine.
650		0	_aTissue engineering.
650	1	4	_aMedicine & Public Health.
650	2	4	_aNeurosurgery.
650	2	4	_aNeurology.
650	2	4	_aRegenerative Medicine/Tissue Engineering.
700	1		_aHoukin, Kiyohiro. _eeditor.
700	1		_aAbe, Koji. _eeditor.
700	1		_aKuroda, Satoshi. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9784431560579
856	4	0	_uhttp://dx.doi.org/10.1007/978-4-431-56059-3
912			_aZDB-2-SME
999			_c1228 _d1228