| 000 | 02468nam a22004455i 4500 | ||
|---|---|---|---|
| 001 | 60204 | ||
| 005 | 20200226102345.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 161209s2017 gw | s |||| 0|eng d | ||
| 020 |
_a9783319453972 _9978-3-319-45397-2 |
||
| 024 | 7 |
_a10.1007/978-3-319-45397-2 _2doi |
|
| 035 | _a(DE-He213)978-3-319-45397-2 | ||
| 050 | 4 | _aRC261-271 | |
| 072 | 7 |
_aMJCL _2bicssc |
|
| 072 | 7 |
_aMED062000 _2bisacsh |
|
| 082 | 0 | 4 |
_a614.5999 _223 |
| 245 | 1 | 0 |
_aEx Vivo Engineering of the Tumor Microenvironment _h[electronic resource] / _cedited by Amir R. Aref, David Barbie. |
| 264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Humana Press, _c2017. |
|
| 300 |
_aIX, 135 p. 18 illus., 17 illus. in color. _bonline resource. |
||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
||
| 347 |
_atext file _bPDF _2rda |
||
| 490 | 1 |
_aCancer Drug Discovery and Development, _x2196-9906 |
|
| 505 | 0 | _a1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy. . | |
| 520 | _aThis volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aCancer research. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aCancer research. |
| 700 | 1 |
_aAref, Amir R. _eeditor. |
|
| 700 | 1 |
_aBarbie, David. _eeditor. |
|
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319453958 |
| 830 | 0 |
_aCancer Drug Discovery and Development, _x2196-9906 |
|
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-319-45397-2 |
| 912 | _aZDB-2-SME | ||
| 999 |
_c2509 _d2509 |
||