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008 170614s2017 si | s |||| 0|eng d
020 _a9789811038860
_9978-981-10-3886-0
024 7 _a10.1007/978-981-10-3886-0
_2doi
035 _a(DE-He213)978-981-10-3886-0
050 4 _aRB45
072 7 _aMJF
_2bicssc
072 7 _aMED038000
_2bisacsh
082 0 4 _a616.15
_223
245 1 0 _aHematological Disorders in Children
_h[electronic resource] :
_bPathogenesis and Treatment /
_cedited by Eiichi Ishii.
264 1 _aSingapore :
_bSpringer Singapore :
_bImprint: Springer,
_c2017.
300 _aX, 269 p. 24 illus., 6 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPart I: Hematopoiesis -- Hematopoietic Stem Cells -- Part II: White Blood Cell Disorders -- Acute Lymphoblastic Leukemia -- Acute Myeloid Leukemia -- Myelodysplastic syndrome and JMML -- Leukopenia (neutropenia) -- Part III: Red Blood Cell Disorders -- Aplastic Anemia -- Bone marrow failure, TAM -- Part IV: Platelet and Coagulation Disorders -- Immune and inherited thrombocytopenia -- Hemophilia -- Thrombosis -- Part V: Histiocytic Disorders -- Langerhans Cell Histiocytosis -- Hemophagocytic Lymphohistiocytosis, primary -- Hemophagocytic Lymphohistiocytosis, secondary.
520 _aThis book describes the pathogenesis and treatment of several representative hematological disorders in children, with a special focus on genetic and molecular aspects. Research on the pathogenesis of hematological disorders in children has made remarkable strides; especially molecular target therapy has shown outstanding effects in refractory and conventional therapies for childhood leukemia. The findings presented in this book will broaden readers’ understanding and hopefully spark new discussions leading to the development of new therapies including cell therapy and molecular target therapy, allowing clinicians to use more effective and less toxic approaches in the future. Hematological Disorders in Children will appeal to a wide readership, from medical students and beginning investigators to experienced scholars in the field of pediatric hematology and oncology seeking to broaden their understanding and keep up with the latest developments. It will also be of interest to the parents of pediatric patients, and to co-medical staffs.
650 0 _aMedicine.
650 0 _aHematology.
650 0 _aOncology.
650 0 _aPediatrics.
650 1 4 _aMedicine & Public Health.
650 2 4 _aHematology.
650 2 4 _aPediatrics.
650 2 4 _aOncology.
700 1 _aIshii, Eiichi.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789811038853
856 4 0 _uhttp://dx.doi.org/10.1007/978-981-10-3886-0
912 _aZDB-2-SME
999 _c3326
_d3326