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007 cr nn 008mamaa
008 161102s2017 gw | s |||| 0|eng d
020 _a9783319407883
_9978-3-319-40788-3
024 7 _a10.1007/978-3-319-40788-3
_2doi
035 _a(DE-He213)978-3-319-40788-3
050 4 _aRG133.5
072 7 _aMFKC
_2bicssc
072 7 _aHEA039060
_2bisacsh
082 0 4 _a612.6
_223
245 1 0 _aImmune Infertility
_h[electronic resource] :
_bImpact of Immune Reactions on Human Fertility /
_cedited by Walter K.H. Krause, Rajesh K. Naz.
250 _a2nd ed. 2017.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2017.
300 _aXI, 302 p. 33 illus., 19 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPart I Sperm antigens: Proteomics of spermatozoa -- Sperm surface proteome -- Methods of Analysis of Sperm Antigens Related to Fertility -- Sperm functions influenced by immune reactions -- Part II Antisperm antibodies (ASA): The immune privilege of the testis -- Immune chemistry of ASA -- Sperm-specific T cells -- Site and risk factors of ASA production -- Biologic substrates containing ASA -- ASA in the female -- Sperm immobilising ASA -- Part III The clinical impact of sperm antibodies: Autoimmune infertility -- Tests for sperm antibodies -- Impact on fertility outcome -- Sperm antibodies and assisted reproduction -- Treatment of immune infertility -- Part IV Immune contraception: Immunization with Sperm Antigens to Induce Contraception -- Immune contraception in wildlife animals -- Experience from Clinical Trials with Fertility Control Vaccines.
520 _a This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aDermatology.
650 0 _aGeneral practice (Medicine).
650 0 _aGynecology.
650 0 _aReproductive medicine.
650 0 _aUrology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aReproductive medicine.
650 2 4 _aGynecology.
650 2 4 _aUrology.
650 2 4 _aImmunology.
650 2 4 _aGeneral Practice / Family Medicine.
650 2 4 _aDermatology.
700 1 _aKrause, Walter K.H.
_eeditor.
700 1 _aNaz, Rajesh K.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319407869
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-40788-3
912 _aZDB-2-SME
999 _c3787
_d3787