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008 170515s2017 si | s |||| 0|eng d
020 _a9789811039782
_9978-981-10-3978-2
024 7 _a10.1007/978-981-10-3978-2
_2doi
035 _a(DE-He213)978-981-10-3978-2
050 4 _aRC254-282
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a616.994
_223
245 1 0 _aPersonalized Management of Gastric Cancer
_h[electronic resource] :
_bTranslational and Precision Medicine /
_cedited by Jia Wei, Baorui Liu.
264 1 _aSingapore :
_bSpringer Singapore :
_bImprint: Springer,
_c2017.
300 _aVIII, 227 p. 34 illus., 32 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aMolecular pathology of hereditary gastric cancer -- Genetics and molecular signature of gastric cancer -- Circulating tumor cells in gastric cancer -- Customized chemotherapy in advanced gastric cancer -- Targeted therapy in advanced gastric cancer -- Laparoscopic surgery and robotic surgery -- Radiotherapy in peritoneal metastatic gastric cancer -- Personalized intraperitoneal strategy in gastric cancer -- Checkpoint blockade therapy of gastric cancer -- Adoptive cell therapy of gastric cancer -- Combinational immunotherapy of gastric cancer -- Use of Nanomedicine in the diagnosis of gastric cancer -- Systemic drug delivery -- Local drug delivery -- Drug delivery in synergistic combination with other treatments.
520 _aThis book offers essential information on basic and translational research in gastric cancer, while also illustrating potential opportunities for its application in clinical practice. Gastric cancer is the fourth-most-common cancer globally and the second-leading cause of cancer deaths. It is known to be a heterogeneous disease with varied responses to “one-size-fits-all” treatments. Expanding our knowledge of cancer cell genetics may help us to explore more effective treatments in gastric cancer. The research on molecular mechanisms and its clinical applications, both presented here, will help readers gain an in-depth understanding of gastric cancer and its effective treatment. The book’s four sections cover personalized medicine, precise regional therapy, immunotherapy and nanomedicine in gastric cancer. Each part presents the state of art, recent advances and the authors’ experiences. Moreover, several interesting cases are described to demonstrate how gastric cancer patients benefit from translational research. This informative and attractively presented book on precision treatment in gastric cancer, including experimental findings and clinical treatment options, offers a valuable resource for oncologists and graduate students working in the field of gastric cancer. Jia Wei, MD, PhD, is an associate professor at Nanjing University and the vice director of Clinical Cancer Institute of Nanjing University. She is now working as an oncologist in the Comprehensive Cancer Center, Affiliated Drum Tower Hospital to Medical School of Nanjing University. Baorui Liu, MD, PhD, is a professor at Nanjing University and director of the Clinical Cancer Institute of Nanjing University. He is also the director of the Comprehensive Cancer Center of Drum Tower Hospital.
650 0 _aMedicine.
650 0 _aGastroenterology.
650 0 _aOncology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOncology.
650 2 4 _aGastroenterology.
700 1 _aWei, Jia.
_eeditor.
700 1 _aLiu, Baorui.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789811039775
856 4 0 _uhttp://dx.doi.org/10.1007/978-981-10-3978-2
912 _aZDB-2-SME
999 _c6430
_d6430