000 02676nam a22005055i 4500
001 59952
005 20200226102619.0
007 cr nn 008mamaa
008 161128s2017 gw | s |||| 0|eng d
020 _a9783319280400
_9978-3-319-28040-0
024 7 _a10.1007/978-3-319-28040-0
_2doi
035 _a(DE-He213)978-3-319-28040-0
050 4 _aRC927-927.5
072 7 _aMJM
_2bicssc
072 7 _aMED083000
_2bisacsh
082 0 4 _a616.723
_223
100 1 _aChu, Cong-Qiu.
_eauthor.
245 1 0 _aTargeting the IL-17 Pathway in Inflammatory Disorders
_h[electronic resource] /
_cby Cong-Qiu Chu.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Adis,
_c2017.
300 _aXV, 102 p. 6 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aIntroduction -- Overview of IL-17 family.-Il-17 in host defense -- Th17 cells: differentiation and regulation -- The role of the IL-17/Th17 pathway in the pathogenesis of autoimmune inflammatory diseases -- Therapeutic applications: strategies and molecules targeting the IL-17/Th17 pathway -- Concluding remarks.
520 _aThis book provides an overview of the discovery and structure of IL-17, including its pathogenesis and role in chronic inflammation and autoimmunity. To capture the latest developments and product approvals the book also discusses the therapeutic advances and looks at emerging therapies targeting the IL-17 pathway. IL-17 is a pro-inflammatory cytokine that has a key role in inflammation, autoimmunity, and host defense in a number of inflammatory disorders such as rheumatoid arthritis, psoriatic arthritis and psoriasis, ankylosing spondylitis, multiple sclerosis, and inflammatory bowel disease. The discovery of the IL-17-Th17 pathway has seen exciting development in the field of immunology and inflammation research, which has led to a number of recent regulatory approvals.
650 0 _aMedicine.
650 0 _aDermatology.
650 0 _aPublic health.
650 0 _aRheumatology.
650 0 _aPrimary care (Medicine).
650 0 _aPharmacotherapy.
650 1 4 _aMedicine & Public Health.
650 2 4 _aRheumatology.
650 2 4 _aDermatology.
650 2 4 _aPharmacotherapy.
650 2 4 _aPrimary Care Medicine.
650 2 4 _aPublic health.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783319280394
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-28040-0
912 _aZDB-2-SME
999 _c8033
_d8033