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008			170711s2017 si | s |||| 0|eng d
020			_a9789811027444 _9978-981-10-2744-4
024	7		_a10.1007/978-981-10-2744-4 _2doi
035			_a(DE-He213)978-981-10-2744-4
050		4	_aRC681-688.2
072		7	_aMJD _2bicssc
072		7	_aMED010000 _2bisacsh
082	0	4	_a616.12 _223
245	1	0	_aTherapeutic Angiogenesis _h[electronic resource] / _cedited by Yukihito Higashi, Toyoaki Murohara.
264		1	_aSingapore : _bSpringer Singapore : _bImprint: Springer, _c2017.
300			_aVI, 266 p. 57 illus., 37 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aChapter 1: Introduction Section: Over View of Therapeutic Angiogenesis -- Part I : Cell Therapy -- Chapter 2: Autologous Bone Marrow Mononuclear Cell Implantation in Extremities with Critical Limb Ischemia -- Chapter 3: Peripheral Blood Mononuclear Cells for Limb Ischemia -- Chapter 4: Endothelial Progenitor Cells for Ischemic Diseases -- Chapter 5: Therapeutic Angiogenesis With Adipose Tissue-derived Regenerative Cells -- Chapter 6: Cell Therapy for Ischemic Heart Disease -- Chapter 7: Angiogenic Therapy for Ischemic Cardiomyopathy with Cell Sheet Technology -- Part II: Gene Therapy -- Chapter 8: The Role of VEGF in Extremities -- Chapter 9: HGF Gene Therapy for Therapeutic Angiogenesis in Peripheral Artery Disease -- Chapter 10: Fibroblast Growth Factor in Extremities -- Part III: Other Therapy -- Chapter 11: Low-intensity Pulsed Ultrasound -- Chapter 12: Low-energy Extracorporeal Shock Wave Therapy -- Chapter 13: Granulocyte-Colony Stimulating Factor -- Chapter 14: Waon Therapy: Effect of Thermal Stimuli on Angiogenesis -- Chapter 15: Exercise -- Chapter 16: Nanoparticle-mediated Endothelial Cell-selective Drug Delivery System.
520			_aThe book discusses recent findings and current perspectives on therapeutic angiogenesis. Studies have shown that therapies such as cell implantation and transfer of gene encoding for angiogenic growth factors are effective in improving symptoms in patients with critical limb ischemia, who previously had no treatment option other than amputation. The book discusses these therapies and presents data collected in clinical studies over the past decade. Despite significant advances in therapeutic angiogenesis since the first clinical studies in the early 21st century, it has been largely ignored in the literature. This comprehensive book fills that gap, making it a valuable resource for both researchers and practitioners alike.
650		0	_aMedicine.
650		0	_aCardiology.
650		0	_aRegenerative medicine.
650		0	_aTissue engineering.
650	1	4	_aMedicine & Public Health.
650	2	4	_aCardiology.
650	2	4	_aRegenerative Medicine/Tissue Engineering.
700	1		_aHigashi, Yukihito. _eeditor.
700	1		_aMurohara, Toyoaki. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789811027437
856	4	0	_uhttp://dx.doi.org/10.1007/978-981-10-2744-4
912			_aZDB-2-SME
999			_c8164 _d8164