Patient-Derived Mouse Models of Cancer (Post nr. 6331)

MARC-detaljer
000 -LEADER
fixed length control field	04659nam a22004575i 4500
001 - CONTROL NUMBER
control field	60476
005 - DATE AND TIME OF LATEST TRANSACTION
control field	20200226102528.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field	cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field	170802s2017 gw \| s \|\|\|\| 0\|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number	9783319574240
--	978-3-319-57424-0
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code	10.1007/978-3-319-57424-0
Source of number or code	doi
035 ## - SYSTEM CONTROL NUMBER
System control number	(DE-He213)978-3-319-57424-0
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number	RC254-282
072 #7 - SUBJECT CATEGORY CODE
Subject category code	MJCL
Source	bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code	MED062000
Source	bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number	616.994
Edition number	23
245 10 - TITLE STATEMENT
Title	Patient-Derived Mouse Models of Cancer
Medium	[electronic resource] :
Remainder of title	Patient-Derived Orthotopic Xenografts (PDOX) /
Statement of responsibility, etc.	edited by Robert M. Hoffman.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture	Cham :
Name of producer, publisher, distributor, manufacturer	Springer International Publishing :
--	Imprint: Humana Press,
Date of production, publication, distribution, manufacture, or copyright notice	2017.
300 ## - PHYSICAL DESCRIPTION
Extent	XVI, 296 p. 60 illus., 50 illus. in color.
Other physical details	online resource.
336 ## - CONTENT TYPE
Content type term	text
Content type code	txt
Source	rdacontent
337 ## - MEDIA TYPE
Media type term	computer
Media type code	c
Source	rdamedia
338 ## - CARRIER TYPE
Carrier type term	online resource
Carrier type code	cr
Source	rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type	text file
Encoding format	PDF
Source	rda
490 1# - SERIES STATEMENT
Series statement	Molecular and Translational Medicine,
International Standard Serial Number	2197-7852
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note	In memorium: Jorgen Rygaard (1934-2016) Father of patient derived mouse models of cancer and modern cancer research -- The revival of patient-derived mouse models of cancer: way back to the future -- Patient-derived xenograft models for human cancer, The Freiburg experience -- From Ectopic to Orthotopic Tumor Grafting Sites: Evidence for a Critical Role of the Host Tissue Microenvironment for the Actual Expression of the Malignant Phenotype -- The Effects of the Organ Microenvironment on Metastatic-Cell Gene Signatures -- Techniques for surgical orthotopic implantation of human tumors to immunodeficient mice -- The first patient-derived orthotopic xenograft (PDOX) mouse models of cancer: Cancer of the colon, pancreas, lung, breast, ovary, and mesothelioma -- Patient-derived xenograft models of prostate cancer -- Patient-Derived Mouse Models of Sarcoma -- Cervical cancer patient-derived orthotopic xenograft (PDOX) models -- The use of pediatric patient-derived xenografts for identifying novel agents and combinations -- Development of Orthotopic and Spontaneous Metastatic Human Tumor Xenograft Models for Experimental Therapeutics -- Use of patient-derived orthotopic xenografts (PDOX) to evaluate transformative cancer therapeutics -- Fluorescent protein-expressing transgenic nude mice as hosts for patient tumors -- Fluorescence imaging of tumors in human patient-derived orthotopic xenograft (PDOX) mouse models: The iPDOX model -- The use of patient-derived orthotopic xenograft (PDOX) models to develop curative fluorescence-guided surgery of cancer.-Molecular characteristics of patient-derived tumor xenografts: genomic similarity to patient tumors and relevance for biomarker discovery -- Complementarity of patient-derived orthotopic xenografts (PDOX) models and molecular profiling for optimal therapy -- 3D Cell Culture Models -- Why patient derived mouse models need to be orthotopic -- Foreward: The future of patient-derived models of cancer. .
520 ## - SUMMARY, ETC.
Summary, etc.	This text highlights seminal discoveries and also provides comprehensive and state-of the-art approach to mouse models of human patient tumors. These areas include training, basic techniques, as well as general troubleshooting. Subsequent chapters focus on the different mouse models of patient tumors including the various strains of immunodeficient mice currently available and the transplantation techniques that can be used as well as state-of-the-art imaging techniques. Practical applications of the models from drug discovery, genome analysis to personalized treatment are also covered. Written by experts in that field, each of these sections address these critical issues. A brief review of the existing literature addressing the particular topic follows in each section. Presently, there is no single source to provide information on technique and uses of mouse models of human patient tumors. Patient-Derived Mouse Models of Cancer will satisfy this need for cancer researchers, oncologists, pharmaceutical and biotechnology industry scientists as well as molecular biologists studying in vivo systems.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Cancer research.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Oncology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Medicine & Public Health.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Oncology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element	Cancer research.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name	Hoffman, Robert M.
Relator term	editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element	SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title	Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information	Printed edition:
International Standard Book Number	9783319574233
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title	Molecular and Translational Medicine,
International Standard Serial Number	2197-7852
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier	<a href="http://dx.doi.org/10.1007/978-3-319-57424-0">http://dx.doi.org/10.1007/978-3-319-57424-0</a>
912 ## -
--	ZDB-2-SME

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